Region | incidence (95% UI) | EAPC (95% CI) | prevalence (95% UI) | EAPC (95% CI) | YLDs (95% UI) | EAPC (95% CI) | |||
---|---|---|---|---|---|---|---|---|---|
1990 | 2019 | 1990 | 2019 | 1990 | 2019 | ||||
ASR per 100,000 | ASR per 100,000 | ASR per 100,000 | ASR per 100,000 | ASR per 100,000 | ASR per 100,000 | ||||
Global | 118.66 (90.89–154.47) | 102 (78.66–130.57) | − 0.41 (-0.54–0.28) | 26.79 (22.08–32.61) | 24.88 (20.79–29.88) | − 0.26 (-0.35–0.17) | 5.73 (3.48–8.67) | 5.02 (3.11–7.69) | − 0.37 (− 0.49–0.25) |
Africa | 137.63 (84.52–240.29) | 76.24 (58.21–98.45) | − 1.42 (− 1.96–0.87) | 28.11 (20.6–40.53) | 21.19 (17.33–26.44) | − 0.64 (− 0.91–0.36) | 6.53 (3.57–11.85) | 3.87 (2.43–5.74) | − 1.25 (− 1.73–0.76) |
African Region | 147.81 (88.87–263.02) | 76.66 (58.11–99.31) | − 1.65 (− 2.29–1.02) | 30.62 (22.34–44.56) | 22.46 (18.41–27.99) | − 0.73 (− 1.04–0.42) | 7.04 (3.79–12.97) | 3.95 (2.49–5.87) | − 1.44 (− 2–0.88) |
America | 155.82 (116.92–204.74) | 133.45 (101.2–175.33) | − 0.45 (− 0.57–0.32) | 35.6 (29.5–44.24) | 31.54 (26.33–38.7) | − 0.36 (− 0.46–0.25) | 7.54 (4.53–11.75) | 6.51 (3.94–10.2) | -0.43 (-0.55–0.31) |
Andean Latin America | 107.92 (77.74–158.55) | 76.01 (58.11–100.86) | − 0.82 (− 1.12–0.51) | 19.62 (14.57–27.64) | 15.1 (11.97–19.47) | − 0.7 (− 0.87–0.52) | 4.98 (2.88–8.3) | 3.56 (2.14–5.56) | − 0.8 (− 1.08–0.52) |
Asia | 93.29 (72.58–118.27) | 96.79 (74.93–123.1) | 0.24 (0.09–0.4) | 22.19 (18.42–26.85) | 24.04 (20.06–28.87) | 0.25 (0.14–0.36) | 4.56 (2.83–6.85) | 4.78 (3–7.22) | 0.26 (0.11–0.4) |
Australasia | 259.68 (184.44–383.09) | 247.36 (176.45–358.3) | − 0.23 (− 0.28–0.18) | 45.44 (33.42–63.59) | 43.94 (32.64–61.17) | − 0.17 (− 0.22–0.12) | 11.86 (6.58–19.68) | 11.33 (6.32–18.8) | − 0.22 (− 0.27–0.17) |
Caribbean | 92.35 (72.27–121.55) | 99.14 (76.58–132.52) | 0.62 (− 0.51–1.76) | 19.11 (15.53–24.02) | 22.73 (17.82–29.45) | 1.03 (0.22–1.86) | 4.37 (2.63–6.84) | 4.79 (2.9–7.44) | 0.71 (-0.38–1.82) |
Central Asia | 128.83 (98.66–171.46) | 111.58 (83.94–151.64) | − 1.07 (− 1.54–0.59) | 24.83 (19.46–32.09) | 22.06 (17.32–28.71) | − 0.79 (− 1.11–0.46) | 6 (3.59–9.46) | 5.22 (3.09–8.3) | − 1.02 (− 1.47–0.57) |
Central Europe | 245.68 (181.14–343.07) | 209.61 (152.09–297.79) | − 0.83 (− 1–0.66) | 47.26 (36.39–62.94) | 40.02 (30.73–53.43) | − 0.77 (− 0.89–0.66) | 11.44 (6.62–18.57) | 9.74 (5.62–16.03) | − 0.83 (− 0.99–0.66) |
Central Latin America | 151.56 (115.21–198.14) | 121.69 (92.42–161.18) | − 0.02 (− 0.28–0.24) | 33.46 (27.17–41.59) | 26.53 (21.61–33.21) | − 0.01 (− 0.26–0.24) | 7.27 (4.39–11.32) | 5.82 (3.51–9.16) | − 0.02 (− 0.27–0.24) |
Central Sub-Saharan Africa | 73.6 (51.32–114.33) | 53.99 (41.48–71.82) | − 2.46 (− 4.28–0.61) | 16.42 (12.24–23.35) | 16.01 (11.51–25.08) | − 1 (-2.12–0.13) | 3.55 (2.09–6.01) | 2.77 (1.74–4.17) | − 2.16 (− 3.84–0.46) |
Commonwealth High Income | 142.31 (106.01–195.83) | 136.49 (100.89–187.77) | − 0.21 (− 0.28–0.14) | 26.87 (20.8–35.28) | 26.32 (20.4–34.56) | − 0.13 (− 0.18–0.07) | 6.6 (3.86–10.55) | 6.36 (3.74–10.27) | − 0.19 (− 0.26–0.13) |
Commonwealth Low Income | 81.66 (60.92–110.22) | 73.28 (56.56–93.24) | − 1.31 (− 2.09–0.53) | 21.02 (17.14–26.41) | 19.93 (16.57–24.61) | − 0.92 (− 1.33–0.51) | 4.07 (2.5–6.13) | 3.7 (2.33–5.56) | − 1.24 (− 1.95–0.53) |
Commonwealth Middle Income | 101.44 (78.7–130.05) | 95.87 (73.92–122.43) | − 0.03 (− 0.15–0.09) | 23.81 (19.92–28.42) | 24.56 (20.72–29.44) | 0.21 (0.09–0.34) | 4.94 (3.06–7.26) | 4.77 (2.96–7.2) | 0.03 (− 0.09–0.15) |
East Asia | 72.86 (53.73–99.57) | 86.42 (63.71–115.38) | 0.09 (− 0.26–0.45) | 18.32 (15.34–22.32) | 23.16 (19.7–27.78) | 0.41 (0.09–0.73) | 3.61 (2.22–5.53) | 4.37 (2.66–6.73) | 0.19 (− 0.15–0.53) |
East Asia & Pacific—WB | 84.9 (64.73–111.33) | 89.37 (67.09–116.57) | − 0.13 (− 0.37–0.11) | 20.36 (17.04–24.6) | 22.43 (18.93–26.98) | 0.05 (− 0.17–0.27) | 4.16 (2.54–6.37) | 4.44 (2.7–6.78) | − 0.07 (− 0.31–0.16) |
Eastern Europe | 246.75 (189.71–327.46) | 189.92 (145.99–250.84) | − 0.97 (− 1.12–0.81) | 49.28 (39.18–63.03) | 38.58 (30.87–49.16) | − 0.88 (− 1.03–0.73) | 11.58 (6.83–18.14) | 8.95 (5.38–13.98) | − 0.95 (− 1.1–0.79) |
Eastern Mediterranean Region | 107.69 (81.71–146.33) | 106.61 (77.77–154.02) | 1.61 (1.03–2.18) | 26.58 (18.7–42.41) | 25.35 (18.22–37.8) | 0.65 (0.31–1) | 5.29 (3.32–8.18) | 5.19 (3.12–8.27) | 1.42 (0.89–1.95) |
Eastern Sub-Saharan Africa | 257.97 (125.49–546.66) | 78.33 (59.97–100.85) | − 2.54 (− 3.59–1.48) | 45.73 (27.81–78.79) | 24.71 (19.08–35.67) | − 1.28 (− 1.83–0.74) | 11.94 (5.59–25.82) | 4.11 (2.62–6.07) | − 2.26 (− 3.2–1.31) |
Europe | 173.11 (130.28–231.42) | 138.44 (104.23–187.88) | − 0.99 (− 1.08–0.89) | 34.3 (27.12–43.96) | 27.7 (22.07–35.37) | − 0.91 (− 0.98–0.84) | 8.11 (4.81–12.71) | 6.5 (3.86–10.22) | − 0.97 (-1.06–0.88) |
Europe & Central Asia—WB | 170.06 (128.06–226.95) | 135.79 (102.15–183.85) | − 1.02 (− 1.12–0.93) | 33.78 (26.73–43.26) | 27.29 (21.7–34.77) | − 0.93 (− 1–0.86) | 7.97 (4.73–12.47) | 6.38 (3.79–10.01) | − 1 (− 1.1–0.91) |
European Region | 169.91 (127.94–226.8) | 135.66 (102.02–183.74) | − 1.02 (− 1.11–0.92) | 33.73 (26.69–43.2) | 27.26 (21.68–34.74) | − 0.93 (-0.99–0.86) | 7.97 (4.73–12.46) | 6.38 (3.79–10.01) | − 1 (− 1.09–0.91) |
High-income Asia Pacific | 145.91 (107.08–200.81) | 130.41 (94.96–180.97) | − 0.55 (− 0.66–0.44) | 29.78 (23.73–38.99) | 26.26 (20.75–34.69) | − 0.59 (− 0.69–0.5) | 6.89 (4.05–11.03) | 6.14 (3.59–10.01) | − 0.56 (− 0.66–0.45) |
High-income North America | 178.07 (130.94–238) | 154.82 (115.59–206.09) | − 0.9 (-1.19–0.61) | 41.12 (34.09–51.61) | 38.28 (32.11–47.01) | − 0.56 (− 0.8–0.32) | 8.65 (5.15–13.83) | 7.64 (4.65–12.04) | − 0.82 (− 1.09–0.54) |
Latin America & Caribbean—WB | 138.72 (104.77–180.41) | 118.39 (89.47–155.75) | − 0.18 (− 0.36–0) | 29.62 (24–36.96) | 25.72 (21.03–31.85) | − 0.12 (− 0.26–0.02) | 6.61 (3.99–10.33) | 5.66 (3.44–8.85) | − 0.17 (− 0.34–0.01) |
Middle East & North Africa—WB | 107.81 (83.22–138.57) | 103.78 (75.44–146.19) | 1.91 (1.22–2.61) | 26.34 (18.61–41.88) | 23.58 (16.81–35.05) | 0.77 (0.32–1.23) | 5.3 (3.38–8.07) | 4.99 (2.98–8.07) | 1.7 (1.05–2.36) |
North Africa and Middle East | 108.24 (81.88–147.43) | 108.69 (76.81–161.3) | 1.52 (0.9–2.13) | 26.48 (18.03–43.22) | 24.82 (17.01–38.3) | 0.57 (0.19–0.96) | 5.31 (3.34–8.25) | 5.24 (3.08–8.58) | 1.34 (0.77–1.91) |
North America | 178.04 (130.92–237.96) | 154.81 (115.58–206.08) | − 0.9 (− 1.19–0.61) | 41.11 (34.08–51.6) | 38.27 (32.1–47) | − 0.56 (− 0.8–0.32) | 8.64 (5.15–13.83) | 7.64 (4.65–12.04) | − 0.81 (− 1.09–0.54) |
Oceania | 60.22 (46.56–77.9) | 66.13 (50.37–86.16) | − 0.01 (− 0.61–0.6) | 13.48 (11.08–16.6) | 15.43 (12.7–19.04) | 0.26 (− 0.1–0.63) | 2.9 (1.78–4.48) | 3.21 (1.99–4.94) | 0.04 (− 0.52–0.61) |
Region of the Americas | 155.82 (116.92–204.74) | 133.45 (101.2–175.33) | − 0.45 (− 0.57–0.32) | 35.6 (29.5–44.24) | 31.54 (26.33–38.7) | − 0.36 (− 0.46–0.25) | 7.54 (4.53–11.75) | 6.51 (3.94–10.2) | − 0.43 (− 0.55–0.31) |
South–East Asia Region | 99.09 (76.77–126.29) | 91.74 (70.72–116.55) | − 0.31 (− 0.52–0.11) | 23.26 (19.37–27.63) | 23.01 (19.31–27.67) | − 0.09 (− 0.24–0.05) | 4.82 (2.99–7.08) | 4.54 (2.81–6.88) | − 0.26 (− 0.45–0.07) |
South Asia | 98.48 (76.1–125.13) | 95.79 (73.83–122.92) | − 0.12 (− 0.31–0.08) | 22.96 (19.15–27.5) | 24.19 (20.4–28.99) | 0.16 (0–0.31) | 4.78 (2.97–7.11) | 4.74 (2.94–7.18) | − 0.05 (− 0.24–0.14) |
South Asia—WB | 101.19 (78.51–129.72) | 99.37 (75.91–127.3) | − 0.04 (− 0.23–0.14) | 23.82 (19.74–29.08) | 25.08 (21–30.06) | 0.16 (0.02–0.29) | 4.92 (3.05–7.24) | 4.92 (3.05–7.3) | 0.01 (− 0.16–0.18) |
Southeast Asia | 92.8 (71.14–120.41) | 75.42 (58.22–95.92) | − 0.69 (− 1.01–0.37) | 21.35 (17.58–26.01) | 18.11 (14.99–22.03) | − 0.62 (− 0.8–0.45) | 4.5 (2.79–6.73) | 3.69 (2.28–5.65) | − 0.68 (− 0.97–0.39) |
Southern Latin America | 152.5 (112.01–212.65) | 150.6 (110.15–208.48) | − 0.22 (− 0.3–0.13) | 28.23 (21.68–37.9) | 27.69 (21.21–37.21) | − 0.23 (− 0.3–0.16) | 7.04 (4.04–11.44) | 6.95 (4.03–11.26) | − 0.22 (− 0.3–0.14) |
Southern Sub− Saharan Africa | 97.4 (73.27–124.84) | 80.11 (60.31–102.43) | − 0.51 (− 0.68–0.35) | 25.32 (21.39–30.38) | 20.64 (17.49–24.66) | − 0.44 (− 0.66–0.23) | 4.87 (2.97–7.41) | 4 (2.43–6.06) | − 0.49 (− 0.67–0.32) |
Sub− Saharan Africa—WB | 154.62 (90.87–283.64) | 78.55 (59.5–101.71) | − 1.6 (− 2.2–0.99) | 31.66 (22.76–46.6) | 23.17 (18.98–28.95) | − 0.67 (− 0.97–0.37) | 7.35 (3.91–13.88) | 4.06 (2.56–6.02) | − 1.38 (− 1.92–0.85) |
Tropical Latin America | 139.2 (103.32–185.7) | 120.92 (89.44–162.49) | − 0.44 (− 0.5–0.39) | 31.75 (26.07–39.07) | 27.77 (22.73–34.21) | − 0.4 (− 0.49–0.32) | 6.73 (4.05–10.56) | 5.87 (3.52–9.13) | − 0.43 (− 0.49–0.37) |
Western Europe | 122.36 (92.87–164.09) | 108.26 (80.2–145.92) | − 0.63 (− 0.71–0.55) | 24.23 (19.2–31.07) | 21.47 (16.82–27.84) | − 0.63 (− 0.71–0.55) | 5.74 (3.44–9.15) | 5.08 (3–8.18) | − 0.63 (− 0.7–0.55) |
Western pacific region | 84.64 (64.5–112.5) | 91.92 (68.82–120.42) | − 0.07 (− 0.34–0.2) | 20.21 (16.91–24.64) | 23.05 (19.47–27.77) | 0.14 (− 0.11–0.39) | 4.14 (2.55–6.31) | 4.57 (2.76–6.97) | − 0.01 (− 0.27–0.25) |
Western Sub− Saharan Africa | 87.86 (64.38–118.08) | 84.8 (62.91–111.95) | − 0.02 (− 0.31–0.28) | 23.62 (19.98–28.05) | 24.57 (20.96–28.94) | 0.24 (0.11–0.36) | 4.44 (2.69–6.64) | 4.38 (2.7–6.57) | 0.05 (− 0.2–0.3) |
World bank high income | 153.52 (114.72–205.55) | 135.68 (101.35–181.43) | − 0.66 (− 0.8–0.52) | 32.03 (25.86–41.01) | 28.84 (23.28–36.75) | − 0.58 (− 0.7–0.46) | 7.28 (4.31–11.56) | 6.46 (3.84–10.31) | − 0.64 (− 0.78–0.51) |
World bank low income | 183.89 (97.66–365.77) | 87.37 (64.54–119.42) | − 1.54 (− 2.38–0.7) | 36.37 (23.24–62.01) | 25.76 (19.29–38.08) | − 0.72 (− 1.13–0.32) | 8.67 (4.35–17.62) | 4.5 (2.8–6.88) | − 1.36 (− 2.1–0.61) |
World bank lower middle income | 99.84 (77.77–127.52) | 92.5 (72.18–117.5) | − 0.13 (− 0.28–0.02) | 23.18 (19.21–27.85) | 22.99 (19.29–27.45) | 0.01 (− 0.07–0.09) | 4.85 (2.99–7.14) | 4.56 (2.82–6.79) | − 0.09 (− 0.22–0.04) |
World bank upper middle income | 108.95 (83.6–139.83) | 103.83 (78.22–135.38) | − 0.1 (− 0.24–0.03) | 25.14 (20.77–30.57) | 24.99 (20.87–30.34) | − 0.04 (− 0.17–0.09) | 5.29 (3.21–8.16) | 5.1 (3.1–7.85) | − 0.08 (− 0.21–0.05) |