Table 1 Eligibility criteria

Population

• Age ≥ 16 years (working age)

• Children (age < 16 years)

Major trauma defined as:

• Injury Severity Score (ISS) of ≥ 16

• Abbreviated Injury Scale (AIS) ≥ 3 and at least one other injury

• Studies that include more than 5% of patients with ISS < 16

• Other injuries: frailty fracture, mono injuries such as isolated facial fractures, isolated closed fractures or spinal injuries, malignant disease, amputations for other reasons than due to the major trauma (e.g., diabetes mellitus), war related injuries, burns as well as psychological trauma (if not related to the major physical trauma)

• Use of other score to determine major trauma which could not be translated into ISS (e.g., Hannover Score for Polytrauma Outcome, New Injury Severity Score)

Intervention

• Any intervention is eligible including but not limited to any clinical, behavioral, and multidisciplinary interventions

Comparison

• Any comparison is eligible including

Predictive factors

• Any factors that affect the ability to RTW

• Factors affecting other related outcomes such as disability

Outcome

• RTW or related concepts such as ability to work, time of sick leave or others

• Studies that merely investigate the proportion of those returning to work without investigation of the influencing factors

Study designs

• Any interventional and observational study with a comparison

• Editorial notes, comments, case reports/series, abstracts, books, grey literature, systematic reviews