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Table 1 Showing baseline characteristics of those who died by day 28 compared to those who survived to day 28

From: Early fluid balance and mortality following extracorporeal cardiopulmonary resuscitation: a high volume, single center study

 

Entire Cohort

(n = 100)

Dead at day 28 (n = 51)

Alive at day 28 (n = 49)

p value

Age, Years (mean, SD)

48.9 (14.1)

48.3 (15.2)

49.5 (12.9)

0.68

Male Sex (n, %)

72 / 100 (72.0%)

36 / 51 (70.6%)

36 / 49 (73.5%)

0.75

Weight, kg (mean, SD)

81.1 (18.9)

85.4 (18.7)

77.1 (18.3)

0.04

Pre-Existing Comorbidities, n (%)

MI

4 / 99 (4.0%)

3 / 50 (6.0%)

1 / 49 (2.0%)

0.62

Congestive Cardiac Failure

9/ 99 (9.1%)

3 / 50 (6.0%)

6 / 49 (12.2%)

0.47

PVD

2 / 99 (2.0%)

2 / 50 (4.0%)

0 / 49 (0.0%)

0.50

Connective Tissue Disease

5 / 99 (5.1%)

0 / 50 (0.0%)

5 / 49 (10.2%)

0.053

Diabetes Mellitus a

14 / 99 (14.1%)

11 / 50 (22.0%)

3 / 49 (6.1%)

0.023

Diagnosis, n (%)

AMI

47 / 100 (47.0%)

22 / 51 (43.1%)

25 / 49 (51.0%)

0.43

Myocarditis

3 / 100 (3.0%)

1 / 51 (2.0%)

2 / 49 (4.1%)

0.97

Primary Arrhythmia

14 / 100 (14.0%)

9 / 51 (17.6%)

5 / 49 (10.2%)

0.28

Acute Decompensated Heart Failure

3 / 100 (4.0%)

1 / 51 (2.0%)

2 / 49 (4.1%)

0.97

PE

9 / 100 (9.0%)

4 / 51 (7.8%)

5 / 49 (10.2%)

0.95

Toxic

3 / 100 (3.0%)

1 / 51 (2.0%)

2 / 49 (4.1%)

0.97

Cardiac Arrest Characteristics, n (%)

OHCA

54 / 100 (54.0%)

33 / 51 (64.7%)

21 / 49 (42.9%)

0.03

Witnessed

81 / 99 (81.8%)

37 / 50 (74.0%)

44 / 49 (89.8%)

0.042

Bystander CPR

99 / 99 (100.0%)

50 / 50 (100.0%)

49 / 49 (100.0%)

1.00

Shockable Initial Rhythm

51 / 96 (53.1%)

26 / 51 (52%)

25 / 45 (55.6%)

0.73

Low Flow Time, minutes (Median, IQR)b

52.5 (39–76)

60 (40–80)

45 (37–73)

0.65

Any ROSCc

33 / 97 (34.0%)

11 / 49 (22.4%)

22/48 (45.8%)

0.015

Biochemical parameters closest to ECMO cannulation

pH (mean, SD)

7.01 (0.29)

6.91 (0.28)

7.11 (0.27)

0.007

Bicarbonate, mmol/L (mean, SD)

16.2 (6.2)

15.1 (5.8)

17.2 (6.5)

0.19

Lactate, mmol/L (mean, SD)

9.8 (5.6)

10.7 (5.2)

9.01 (5.8)

0.22

  1. MI = myocardial infarction, PVD = peripheral vascular disease, AMI = acute myocardial infarction, PE = pulmonary embolus, OHCA = out-of-hospital cardiac arrest, ROSC = return of spontaneous circulation ECMO = extra corporeal membrane oxygenation
  2. a This includes all types of diabetes mellitus
  3. b Low flow time is the time from commencement of chest compressions to ECMO cannulation
  4. c ROSC is assumed if there is documented evidence of ROSC at any point. This did not have to be sustained